Swedish COVID-19 Sample Collection Database

Home / Stockholms Medicinska Biobank / Immunologiskt svar efter vaccinering med mRNA vaccin mot covid-19, Comirnaty, hos immunsupprimerade och immunkompetenta personer- en öppen icke randomiserad multicenterstudie i Fas IV

Collection

Immunologiskt svar efter vaccinering med mRNA vaccin mot covid-19, Comirnaty, hos immunsupprimerade och immunkompetenta personer- en öppen icke randomiserad multicenterstudie i Fas IV

Description: Phase 4, open, non-randomised cohort study. The Comirnaty vaccine will be administered in two doses. Analyses of blood and saliva related to humoral and cellular response will be carried out. The occurrence of local or systematic reactogenicity, as well as AE/SAE/SUSAR will be evaluated. Samples included in the biobank include plasma, serum, and saliva from 540 patients from 4 different time points (day 0, 10, 21, 35) and matched PBMC from 270 patients.
Acronym:
COVAXID
Biobank:
Stockholms Medicinska Biobank
Local collection ID (within the biobank):
BbK2655

General information

Collection size:
1000 - 10.000 (as of 2021-07-16)
Type:
Disease specific Hospital Sample
Data:
Biological samples Medical records
Start date of sampling:
2021-02-01
End date of sampling:
2021-12-31
Collection preserved at least until:
2026-01-01
Ethical approval number:
2021-00451

Donor information

Number of donors:
100 - 1000
Samples from deceased (autopsy):
no
Samples from minors (<18 years old):
no
Inclusion criteria: 5 groups of immunosuppressed individuals, including Primary Immunodeficiency, HIV, Hematopoietic Stem Cell transplantation/CAR-T, Solid Organ Transplantation and 1 healthy control group.

Sample information

Materials:
Collection contact information
Collection head: Soo Aleman
Contact person: Soo Aleman
soo.aleman@regionstockholm.se
Biobank contact information
Stockholms Medicinska Biobank
Registration number at IVO: 914
biobankstockholm@regionstockholm.se